By C A Bartzokas; G W Smith
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History checklist General • Is the patient immunocompromised (PML) or have they previously had measles (SSPE)? • How old is the patient (SSPE usually develops between the ages of 5 and 15 years)? Specific • Features common to SSPE, PML and CJD are insidious mental changes (memory, confusion, behavioural and personality changes, progressing to a dementing state). • Enquire about involuntary movements, particularly myoclonic jerks (SSPE and CJD). Visual disturbances (hemianopia, visuospatial disorientation, ocular apraxia, and cortical blindness) may be seen in PML and to a lesser extent in CJD.
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Banatvala, J. et al. (1991) Chronic fatigue syndrome: guidelines for research. J. R. Soc. Med. 84: 118–121. , Simkin S. et al. (1996) Cognitive behaviour therapy for chronic fatigue syndrome: a randomised controlled trial. Br. Med. J. 312: 22–26. Shepherd, C. (1995) Myalgic Encephalomyelitis: Post-Viral Fatigue Syndrome. Guidelines for the care of patients, 2nd Edn. E. Association, Stanford le Hope. Wessely, S. (1995) The epidemiology of chronic fatigue syndrome. Epidemiol. Rev. 17: 139–151. , Hotopf, M.
Managing infections : decision-making options in clinical practice by C A Bartzokas; G W Smith