By Ai-Lean Chew, Howard I. Maibach
Irritant dermatitis is a typical situation, accounting for an important percentage of occupational dermis affliction. the new creation of non-invasive epidermis bioengineering know-how has sped up dermatology learn during this box. This e-book contains an exhaustive reference textual content on irritant touch dermatitis, masking all facets of the : medical positive aspects, epidemiology, prevention and remedy, analysis, mechanisms, pathology and regulatory matters. The booklet additionally provides novel in vitro and in vivo learn strategies and findings. As irritant dermatitis impacts a number of specialties, the viewers for this ebook is extensive, together with medical and investigative dermatologists, allergists, toxicologists, pharmaceutical scientists, occupational and environmental physicians, public wellbeing and fitness physicians, cosmetologists and dermis bioengineers.
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Additional resources for Irritant Dermatitis
An essential role for Langerhans cell-derived IL-beta in the initiation of primary immune responses in skin. J Immunol 1993; 150:3698–3704 2 Irritant Contact Dermatitis Versus Allergic Contact Dermatitis 13. Ferguson J, Gibbs JH, Swanson Beck J. Lymphocyte subsets and Langerhans cells in allergic and irritant patch test reactions: histometric studies. Contact Derm 1985; 13:166– 174 14. Flier J, Boorsma DM, Bruynzeel DP, Van Beek PJ, Stoof TJ. Scheper RJ, Willemze R, Tensen CP. The CXCR3 activating chemokines IP-10, Mig, and IP-9 are expressed in allergic but not in irritant patch test reactions.
J Appl Toxicol 2000; 20(4):335–341 11. Emilson A, Lindberg M, Scheynius A. Differential epidermal expression of the invariant chain in allergic and irritant contact dermatitis. Acta Derm Venereol 1998; 78(6):402–407 12. Enk AH, Angeloni VL, Udey MC, Katz SI. An essential role for Langerhans cell-derived IL-beta in the initiation of primary immune responses in skin. J Immunol 1993; 150:3698–3704 2 Irritant Contact Dermatitis Versus Allergic Contact Dermatitis 13. Ferguson J, Gibbs JH, Swanson Beck J.
Necrosis and ulceration may be seen after contact with corrosive materials (Table 1). Symptoms of acute ICD are burning, stinging and soreness of the skin. In ACD pustules, necrosis and ulceration are rarely observed, vesiculation predominates and pruritus is the cardinal symptom. The diagnosis of acute irritant dermatitis to strong agents is usually evident, since the rapid onset of skin changes after exposure points to the causative agent. However, when faced with a subacute or chronic contact dermatitis, the clinician must discriminate between ICD, ACD, or other eczematous conditions through a decision process.
Irritant Dermatitis by Ai-Lean Chew, Howard I. Maibach