By Timothy C. Williams
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Extra info for Chemotaxis: Types, Clinical Significance, and Mathematical Models
Plasticity of cell migration: a multiscale tuning model. J Cell Biol, 2010, Jan 11, 188(1), 11-19. Friedrichson, T; Kurzchalia, TV. Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature, 1998, Aug 20, 394(6695), 802-805. Furlan, F; Orlando, S; Laudanna, C; Resnati, M; Basso, V; Blasi, F; Mondino, A. The soluble D2D3(88-274) fragment of the urokinase receptor inhibits monocyte chemotaxis and integrin-dependent cell adhesion. J Cell Sci, 2004, Jun 15, 117(Pt 14), 2909-2916.
The influence of the shorter forms of uPAR on integrin activity has not been thoroughly studied. , 1999, 2002]. , 2004]. For their part, integrins are not passive but rather affect uPAR expression, distribution and activity. , 1996]. , 2006]. , 1999, 2001a]. , 2006]. uPAR-integrin interactions are positively regulated by the ligands of the integrins. , 2007]. In addition, integrins influence uPAR distribution on the cell surface. , 2000, 2006]. , 1994]. As uPAR partners, the integrins have a notable impact on uPAR activity but can also use uPAR as a tool to control the activity of other integrins.
Degryse, B; Bonaldi, T; Scaffidi, P; Müller, S; Resnati, M; Sanvito, F; Arrigoni, G; Bianchi, ME. The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J Cell Biol, 2001c, Mar 19, 152(6), 1197-1206. Degryse, B; Neels, JG; Czekay, RP; Aertgeerts, K; Kamikubo, Y; Loskutoff, DJ. The low density lipoprotein receptor-related protein is a motogenic 36 Gabriele Eden, Marco Archinti, Federico Furlan et al. receptor for plasminogen activator inhibitor-1.
Chemotaxis: Types, Clinical Significance, and Mathematical Models by Timothy C. Williams